One hundred fifty two 152 dogs of various breeds 0 5 12 4 years of age and weighing 2 1 134 6 lbs 0 95 61 2 kg were enrolled.
Zycortal for dogs side effects.
One hundred thirteen 113 dogs were treated with zycortal suspension and 39 dogs were treated with the active control.
152 dogs of various breeds 0 5 12 4 years of age and weighing 0 95 61 2 kg were enrolled.
Zycortal is a new treatment for addison s disease hypoadrenocorticism in dogs.
Subsequent doses administered and or frequency.
Both groups were administered an initial dose of 2 2 mg kg.
One hundred thirteen 113 dogs were treated with zycortal suspension and 39 dogs were treated with the active control.
Do not use in pregnant dogs or in dogs suffering from congestive heart failure severe renal disease or edema.
Do not use in pregnant dogs or in dogs suffering from congestive heart disease severe renal disease or edema.
The most common side effects with zycortal which may affect more than 1 in 10 dogs are polydipsia increase in water intake and polyuria increase in urine production.
Some patients are more sensitive to the actions of zycortal suspension and may exhibit side effects in an exaggerated degree.
Like other adrenocortical hormones percorten v may cause severe side effects if dosage is too high or prolonged.
Zycortal suspension replaces mineralocorticoids which are deficient in dogs with addison s.
In a laboratory study zycortal suspension was administered via subcutaneous injection to 32 beagle dogs four groups of 8 dogs each at doses of 0 1 3 and 5 times the labeled starting dose 1x 2 2 mg kg once every 21 days for 6 months for a total of 9 injections.
Possible side effects of zycortal suspension include polyuria excessive urination polydipsia excessive thirst increased blood volume edema and cardiac enlargement.
For use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism addison s disease.
Dogs presenting in addisonian crisis must be rehydrated with appropriate intravenous therapy before starting treatment with zycortal suspension.
For the full list of all side effects reported with zycortal see the package leaflet.
It is given by injection at approximately 1 month intervals.
Reduce dosage in dogs showing signs of hypernatremia or hypokalemia.
Both groups were administered an initial dose of 2 2 mg kg.
Excessive weight gain may indicate fluid retention secondary to sodium retention.
